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FRA, 4DN: Denali Therapeutics Inc

22 Dec 2025
LAST:

14.36

CHANGE:
 0.11		OPEN:
14.36		HIGH:
14.36		ASK:
0.00		VOLUME:
350
CHG(%):
0.77		PREV:
14.25		LOW:
14.36		BID:
0.00		 

CHART

RECENT END OF DAY PRICES

DateOpenHighLowCloseVolume
22 Dec 2514.3614.3614.3614.36350
19 Dec 2514.2514.2514.2514.25350
18 Dec 2514.2714.2714.2714.27350
17 Dec 2514.4814.4814.4814.48350
16 Dec 2514.4714.4714.4714.47350
15 Dec 2515.2915.2915.2915.29350
12 Dec 2514.6814.6814.6814.68350
09 Dec 2516.8116.8116.8116.81133
08 Dec 2517.0417.0417.0417.04133
05 Dec 2517.1917.1917.1917.19133

PROFILE

Name:Denali Therapeutics Inc
About:Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
Sector:Healthcare
Industry:Biotechnology
Address:161 Oyster Point Boulevard, South San Francisco, CA, United States, 94080
Website:https://www.denalitherapeutics.com
ISIN:US24823R1059
LEI:549300ZTQ2HO18L3Q830

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FUNDAMENTALS

Trailing P/E:-5.09 
Forward P/E:-6.17 
PEG Ratio:-0.23 
Price to Sales:3,655.64 
Price to Book:1.99 
Return on Assets:-0.25 
Return on Equity:-0.40 
Shares:146.21M 
Market Cap:2.099B 

TECHNICAL INDICATORS

MA5:14.360.0%
MA10:15.286.4%
MA20:15.588.6%
MA50:14.400.3%
MA100:13.377.4%
MA200:13.179.0%
STO9:3.94 
STO14:3.74 
RSI14:33.38 
WPR14:-96.26 
MTM14:-1.55
ROC14:-0.10 
ATR:0.57 
Week High:15.296.5%
Week Low:14.250.8%
Month High:17.1919.7%
Month Low:14.259.0%
Year High:23.1461.2%
Year Low:10.1841.0%
Volatility:36.49