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FRA, 4DN: Denali Therapeutics Inc

05 Nov 2025
LAST:

12.88

CHANGE:
 0.22		OPEN:
12.88		HIGH:
12.88		ASK:
0.00		VOLUME:
280
CHG(%):
1.64		PREV:
13.09		LOW:
12.88		BID:
0.00		 

CHART

RECENT END OF DAY PRICES

DateOpenHighLowCloseVolume
05 Nov 2512.8812.8812.8812.88280
04 Nov 2513.1413.1413.0913.09280
31 Oct 2514.1214.1214.1214.1275
30 Oct 2513.8713.8713.8713.8775
29 Oct 2514.4614.4614.4614.4675
28 Oct 2513.7913.7913.7913.7975
27 Oct 2513.7013.7013.6913.6975
24 Oct 2513.6013.6113.6013.6167
23 Oct 2513.6613.6613.6613.66300
22 Oct 2514.5314.5314.4814.48300

COMPANY PROFILE

Name:Denali Therapeutics Inc
About:Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; DNL343 eIF2B activator program for amyotrophic lateral sclerosis; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 program for MPS IIIA (Sanfilippo Syndrome A); and DNL310 Tividenofusp alfa, an enzyme replacement therapy program for MPS II (Hunter Syndrome). Its Enzyme TransportVehicle (TV) programs include DNL952 for the treatment of Pompe disease; DNL111 for Parkinson's and Gaucher diseases; and DNL622 for Hurler syndrome (MPS I). The company's OTV programs also comprise DNL628 targeting tau for Alzheimer's disease; and DNL422 targeting alpha synuclein for Parkinson's disease, as well as antibody TV program includes DNL921 targeting Abeta for treating Alzheimer's disease. The company was formerly known as SPR Pharma Inc. and changed its name to Denali Therapeutics Inc. in March 2015. Denali Therapeutics Inc. was incorporated in 2013 and is headquartered in South San Francisco, California.
Sector:Healthcare
Industry:Biotechnology
Address:161 Oyster Point Boulevard, South San Francisco, CA, United States, 94080
Website:https://www.denalitherapeutics.com
ISIN:US24823R1059
LEI:549300ZTQ2HO18L3Q830

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FUNDAMENTALS

Trailing P/E:-5.09 
Forward P/E:-6.17 
PEG Ratio:-0.23 
Price to Sales:3,655.64 
Price to Book:1.99 
Return on Assets:-0.25 
Return on Equity:-0.40 
Shares:146.21M 
Market Cap:1.882B 

TECHNICAL INDICATORS

MA5:13.686.3%
MA10:13.766.9%
MA20:13.635.8%
MA50:12.990.9%
MA100:12.592.3%
MA200:13.998.7%
RSI14:54.32
WPR14:-100.00 
MTM14:-0.17
ROC14:-0.01 
ATR:0.46 
Week High:14.4612.3%
Week Low:12.880.0%
Month High:14.7414.5%
Month Low:12.328.7%
Year High:29.73130.9%
Year Low:10.1826.5%
Volatility:22.97